The 24I/O uses the same PCI-424 card that comes with the 2408mk3. You can connect up to four audio interfaces to a PCI-424 in any combination to create a system that fits your needs.

An ideal companion for the 2408
The 24I/O adds 24 channels of high quality analog input and output to your MOTU Audio system. With that much I/O available, you can keep the outputs of your synthesizers and outboard effects patched into your computer at all times. It is a snap to route the output via the PCI-424 Console Software.